The talk discusses web accessibility, focusing on making websites usable for people with disabilities, particularly those who are blind. The speaker, whose mother is blind, emphasizes that accessibility benefits everyone, not just those with permanent disabilities. He covers semantic HTML, ARIA roles, and practical implementations for making web content accessible through screen readers and other assistive technologies.

This talk focuses on how to effectively use HTML to improve website performance and accessibility. The speaker emphasizes the importance of using semantic HTML elements correctly instead of generic div elements, explains how HTML impacts the DOM and accessibility tree, and covers various HTML attributes and resource hints that can optimize page loading.